2 papers
q-bio.PE2025
Mendelian randomization in a multi-ancestry world: reflections and practical advice
Amy M. Mason, Verena Zuber, Gibran Hemani +8
Many Mendelian randomization (MR) papers have been conducted only in people of European ancestry, limiting transportability of results to the global population. Expanding MR to div…
stat.ME2025
Context-stratified Mendelian randomization: exploiting regional exposure variation to explore causal effect heterogeneity and non-linearity
Stephen Burgess, Benjamin A R Woolf, Amy M Mason
Mendelian randomization (MR) uses genetic variants as instrumental variables to make causal claims. Standard MR approaches typically report a single population-averaged estimate, l…