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stat.ME2025
Leveraging external data in the analysis of randomized controlled trials: a comparative analysis
Gopal Kotecha, Daniel E. Schwartz, Steffen Ventz +1
The use of patient-level information from previous studies, registries, and other external datasets can support the analysis of single-arm and randomized controlled trials to evalu…
stat.ME2025
Dynamic borrowing from historical controls via the synthetic prior with covariates in randomized clinical trials
Daniel E. Schwartz, Yuan Ji, Li Wang
Motivated by a rheumatoid arthritis clinical trial, we propose a new Bayesian method called SPx, standing for synthetic prior with covariates, to borrow information from historical…