7 citations · 14 across the 6 of their papers we have counts for
7 papers
Darwinian Genetic Drift
Alexey A. Shadrin, Dmitri V. Parkhomchuk
Genetic drift is stochastic fluctuations of alleles frequencies in a population due to sampling effects. We consider a model of drift in an equilibrium population, with high mutati…
Genetic recombination as DNA repair
Dmitri Parkhomchuk, Alice C. McHardy, Alexey Shadrin
Maintenance of sexual reproduction and genetic recombination imposes physiological costs when compared to parthenogenic reproduction, most prominently: for maintaining the correspo…
Drake's Rule as a Consequence of Approaching Channel Capacity
Alexey A. Shadrin, Dmitri V. Parkhomchuk
How mutations accumulate in genomes is the central question of molecular evolution theories, however our understanding of this process is far from complete. Drake's rule is a notor…
Information Theory of Genomes
Dmitri V. Parkhomchuk
Relation of genome sizes to organisms complexity is still described rather equivocally. Neither the number of genes (G-value), nor the total amount of DNA (C-value) correlates cons…
Genetic Variability of Splicing Sites
Dmitri Parkhomchuk
Splicing sites provide unique statistics in human genome due to their large number and reasonably complete annotation. Analyses of the cumulative SNPs distribution in splicing site…
Di-nucleotide Entropy as a Measure of Genomic Sequence Functionality
Dmitri Parkhomchuk
Considering vast amounts of genomic sequences of mostly unknown functionality, in-silico prediction of functional regions is an important enterprise. Many genomic browsers employ G…