7 papers
Code Sharing in Healthcare Research: A Practical Guide and Recommendations for Good Practice
Lukas Hughes-Noehrer, Matthew J Parkes, Andrew Stewart +8
As computational analysis becomes increasingly more complex in health research, transparent sharing of analytical code is vital for reproducibility and trust. This practical guide,…
Sequential sample size calculations and learning curves safeguard the robust development of a clinical prediction model for individuals
Amardeep Legha, Joie Ensor, Rebecca Whittle +7
When prospectively developing a new clinical prediction model (CPM), fixed sample size calculations are typically conducted before data collection based on sensible assumptions. Bu…
A decomposition of Fisher's information to inform sample size for developing or updating fair and precise clinical prediction models -- Part 3: continuous outcomes
Rebecca Whittle, Richard D Riley, Lucinda Archer +4
Clinical prediction models enable healthcare professionals to estimate individual outcomes using patient characteristics. Current sample size guidelines for developing or updating…
Critical Appraisal of Fairness Metrics in Clinical Predictive AI
João Matos, Ben Van Calster, Leo Anthony Celi +6
Predictive artificial intelligence (AI) offers an opportunity to improve clinical practice and patient outcomes, but risks perpetuating biases if fairness is inadequately addressed…
A general sample size framework for developing or updating a clinical prediction model
Richard D Riley, Rebecca Whittle, Mohsen Sadatsafavi +4
Aims: To propose a general sample size framework for developing or updating a clinical prediction model using any statistical or machine learning method, based on drawing samples f…
A decomposition of Fisher's information to inform sample size for developing fair and precise clinical prediction models -- Part 2: time-to-event outcomes
Richard D Riley, Gary S Collins, Lucinda Archer +9
Background: When developing a clinical prediction model using time-to-event data, previous research focuses on the sample size to minimise overfitting and precisely estimate the ov…