2 papers
cs.LG2026
Chamaileon: Cross-Context Binder Design with Contextualized Modeling and Mixed Sampling
Hengyuan Cao, Shizhuo Cheng, Mingxuan Liu +5
The rapid evolution of generative models has unlocked new potentials in protein binder design, a pivotal task in structural biology, by facilitating end-to-end generation via joint…
cs.AI2025
ProtPainter: Draw or Drag Protein via Topology-guided Diffusion
Zhengxi Lu, Shizhuo Cheng, Yuru Jiang +2
Recent advances in protein backbone generation have achieved promising results under structural, functional, or physical constraints. However, existing methods lack the flexibility…