3 papers
q-bio.BM2025
Molecular Dynamics Simulations of Membrane Selectivity of Star Peptides Across Different Bacterial and Mammalian Bilipids
Amal Jayawardena, Andrew Hung, Greg Qiao +2
Structurally nanoengineered antimicrobial peptide polymers (SNAPPs) are emerging as promising selective agents against bacterial membranes. In this study, we used all atom molecula…
physics.bio-ph2025
Lipidation-induced bacterial cell membrane translocation of star-peptides
Amal Jayawardena, Andrew Hung, Greg Qiao +1
The rapid emergence of multidrug-resistant (MDR) bacteria demands development of novel and effective antimicrobial agents. Structurally Nanoengineered Antimicrobial Peptide Polymer…
cond-mat.soft2024
Bacterial cell death: Atomistic simulations reveal pore formation as a mode of action of structurally nano engineered star peptide polymers
Amal Jayawardena, Andrew Hung, Greg Qiao +1
Multidrug resistance (MDR) to conventional antibiotics is one of the most urgent global health threats, necessitating the development of effective and biocompatible antimicrobial a…