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q-bio.MN2004
Conditional Network Analysis Identifies Candidate Regulator Genes in Human B Cells
Kai Wang, Nilanjana Banerjee, Adam Margolin +4
Cellular phenotypes are determined by the dynamical activity of networks of co-regulated genes. Elucidating such networks is crucial for the understanding of normal cell physiology…
q-bio.MN2004★ 2.5k cited
ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context
Adam A. Margolin, Ilya Nemenman, Katia Basso +5
Background: Elucidating gene regulatory networks is crucial for understanding normal cell physiology and complex pathologic phenotypes. Existing computational methods for the genom…