2.5k citations · 2.5k across the 4 of their papers we have counts for
4 papers
Multivariate dependence and genetic networks inference
Adam A. Margolin, Kai Wang, Andrea Califano +1
A critical task in systems biology is the identification of genes that interact to control cellular processes by transcriptional activation of a set of target genes. Many methods h…
Conditional Network Analysis Identifies Candidate Regulator Genes in Human B Cells
Kai Wang, Nilanjana Banerjee, Adam Margolin +4
Cellular phenotypes are determined by the dynamical activity of networks of co-regulated genes. Elucidating such networks is crucial for the understanding of normal cell physiology…
ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context
Adam A. Margolin, Ilya Nemenman, Katia Basso +5
Background: Elucidating gene regulatory networks is crucial for understanding normal cell physiology and complex pathologic phenotypes. Existing computational methods for the genom…
On The Reconstruction of Interaction Networks with Applications to Transcriptional Regulation
Adam A. Margolin, Ilya Nemenman, Chris Wiggins +2
A novel information-theoretic method for reconstruction of interaction networks is introduced. We prove that the method is exact for some class of networks. Performance tests on la…