150 citations · 1.6k across the 51 of their papers we have counts for
51 papers
Non-equilibrium chromosome looping via molecular slip-links
C. A. Brackley, J. Johnson, D. Michieletto +4
We propose a model for the formation of chromatin loops based on the diffusive sliding of a DNA-bound factor which can dimerise to form a molecular slip-link. Our slip-links mimic…
Diffusion-based DNA target colocalization by thermodynamic mechanisms
Antonio Scialdone, Mario Nicodemi
In eukaryotic cell nuclei, a variety of DNA interactions with nuclear elements occur, which, in combination with intra- and inter- chromosomal cross-talks, shape a functional 3D ar…
A symmetry breaking mechanism for epithelial cell polarization
A. Veglio, A. Gamba, M. Nicodemi +2
In multicellular organisms, epithelial cells form layers separating compartments responsible for different physiological functions. At the early stage of epithelial layer formation…
Jamming phase diagram for frictional particles
M. Pica Ciamarra, R. Pastore, M. Nicodemi +1
The non-equilibrium transition from a fluid-like state to a disordered solid-like state, known as the jamming transition, occurs in a wide variety of physical systems, such as coll…
Thermodynamic pathways to genome spatial organization in the cell nucleus
Mario Nicodemi, Antonella Prisco
The architecture of the eukaryotic genome is characterized by a high degree of spatial organization. Chromosomes occupy preferred territories correlated to their state of activity…
Mechanics and Dynamics of X-Chromosome Pairing at X Inactivation
A. Scialdone, M. Nicodemi
At the onset of X Chromosomes Inactivation, the vital process whereby female mammal cells equalize X products with respect to males, the X chromosomes are colocalized along their X…