645 citations · 2.1k across the 59 of their papers we have counts for
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Elastic free energy drives the shape of prevascular solid tumors
Kristen L. Mills, Ralf Kemkemer, Shiva Rudraraju +1
It is well established that the mechanical environment influences cell functions in health and disease. Here, we address how the mechanical environment influences tumor growth, in…
The mechano-chemistry of cytoskeletal force generation
Mirko Maraldi, Krishna Garikipati
In this communication, we propose a model to study the non-equilibrium process by which actin stress fibers develop force in contractile cells. The emphasis here is on the non-equi…
A computational study of stress fiber-focal adhesion dynamics governing cell contractility
Mirko Maraldi, Clara Valero, Krishna Garikipati
We apply a recently developed model of cytoskeletal force generation to study a cell intrinsic contractility, as well as its response to external loading. The model is based on a n…
Three-dimensional iso-geometric solutions to general boundary value problems of Toupin's gradient elasticity theory at finite strains
Shiva Rudraraju, Anton van der Ven, Krishna Garikipati
We present, to the best of our knowledge, the first complete three-dimensional numerical solutions to a broad range of boundary value problems for a general theory of finite strain…