3 papers
cs.LG2025
AI-driven software for automated quantification of skeletal metastases and treatment response evaluation using Whole-Body Diffusion-Weighted MRI (WB-DWI) in Advanced Prostate Cancer
Antonio Candito, Matthew D Blackledge, Richard Holbrey +10
Quantitative assessment of treatment response in Advanced Prostate Cancer (APC) with bone metastases remains an unmet clinical need. Whole-Body Diffusion-Weighted MRI (WB-DWI) prov…
cs.CV2025
A weakly-supervised deep learning model for fast localisation and delineation of the skeleton, internal organs, and spinal canal on Whole-Body Diffusion-Weighted MRI (WB-DWI)
A. Candito, A. Dragan, R. Holbrey +6
Background: Apparent Diffusion Coefficient (ADC) values and Total Diffusion Volume (TDV) from Whole-body diffusion-weighted MRI (WB-DWI) are recognized cancer imaging biomarkers. H…
stat.AP2025
Generalizing imaging biomarker repeatability studies using Bayesian inference: Applications in detecting heterogeneous treatment response in whole-body diffusion-weighted MRI of metastatic prostate cancer
Matthew D Blackledge, Konstantinos Zormpas-Petridis, Ricardo Donners +6
The assessment of imaging biomarkers is critical for advancing precision medicine and improving disease characterization. Despite the availability of methods to derive disease hete…