2 papers
cs.LG2025
Disentangling Causal Substructures for Interpretable and Generalizable Drug Synergy Prediction
Yi Luo, Haochen Zhao, Xiao Liang +4
Drug synergy prediction is a critical task in the development of effective combination therapies for complex diseases, including cancer. Although existing methods have shown promis…
q-bio.GN2025
TopoLa: A Universal Framework to Enhance Cell Representations for Single-cell and Spatial Omics through Topology-encoded Latent Hyperbolic Geometry
Kai Zheng, Shaokai Wang, Yunpei Xu +8
Recent advances in cellular research demonstrate that scRNA-seq characterizes cellular heterogeneity, while spatial transcriptomics reveals the spatial distribution of gene express…