2 papers
q-bio.OT2025
Mathematical and Computational Nuclear Oncology: Toward Optimized Radiopharmaceutical Therapy via Digital Twins
Marc Ryhiner, Yangmeihui Song, Babak Saboury +3
This article presents the general framework of theranostic digital twins (TDTs) in computational nuclear medicine, designed to support clinical decision-making and improve cancer p…
physics.med-ph2025
An Overview of Physiologically Based Pharmacokinetic (PBPK) and Population Pharmacokinetic (PopPK) Models
Deni Hardiansyah, Bisma Baron Patrianesha, Kuangyu Shi +3
This review discusses the current applications, advantages, and limitations of PBPK and PopPK models in radiopharmaceutical therapy (RPT). PBPK models simulate radiopharmaceutical…