collaborators

5 papers

physics.med-ph2025

A One Dimensional (1D) Computational Fluid Dynamics Study of Fontan-Associated Liver Disease (FALD)

Yaqi Li, Justin D. Weigand, Charles Puelz +2

Fontan-Associated Liver Disease (FALD) is a disorder arising from hemodynamic changes and venous congestion in the liver. This disease is prominent in patients with hypoplastic lef…

q-bio.QM2025

Deformable Registration of MRA and 4D Flow Images to Facilitate Accurate Estimation of Flow Properties within Blood Vessels

Dan Lior, Craig G. Rusin, Justin Weigand +5

A method is presented for the registration of MRA and 4D Flow images, with the goal of calculating blood flow properties using both modalities simultaneously. In particular, the me…

q-bio.QM2024

Parameter selection and optimization of a computational network model of blood flow in single-ventricle patients

Alyssa M. Taylor-LaPole, L. Mihaela Paun, Dan Lior +3

Hypoplastic left heart syndrome (HLHS) is a congenital heart disease responsible for 23% of infant cardiac deaths each year. HLHS patients are born with an underdeveloped left hear…

q-bio.TO2024

Computational framework for the generation of one-dimensional vascular models accounting for uncertainty in networks extracted from medical images

Michelle A Bartolo, Alyssa M Taylor-LaPole, Darsh Gandhi +9

Patient-specific computational modeling is a popular, non-invasive method to answer medical questions. Medical images are used to extract geometric domains necessary to create thes…

q-bio.TO2024

Fluid-structure interaction simulations for the prediction of fractional flow reserve in pediatric patients with anomalous aortic origin of a coronary artery

Charles Puelz, Craig G. Rusin, Dan Lior +5

Computer simulations of blood flow in patients with anomalous aortic origin of a coronary artery (AAOCA) have the promise to provide insight into this complex disease. They provide…