7 papers
DeepFixel: Crossing white matter fiber identification through spherical convolutional neural networks
Adam M. Saunders, Lucas W. Remedios, Elyssa M. McMaster +6
Diffusion-weighted magnetic resonance imaging allows for reconstruction of models for structural connectivity in the brain, such as fiber orientation distribution functions (ODFs)…
Phenotype discovery of traumatic brain injury segmentations from heterogeneous multi-site data
Adam M. Saunders, Michael E. Kim, Gaurav Rudravaram +8
Traumatic brain injury (TBI) is intrinsically heterogeneous, and typical clinical outcome measures like the Glasgow Coma Scale complicate this diversity. The large variability in s…
Lifespan Pancreas Morphology for Control vs Type 2 Diabetes using AI on Largescale Clinical Imaging
Lucas W. Remedios, Chloe Cho, Trent M. Schwartz +11
Purpose: Understanding how the pancreas changes is critical for detecting deviations in type 2 diabetes and other pancreatic disease. We measure pancreas size and shape using morph…
Data-Driven Abdominal Phenotypes of Type 2 Diabetes in Lean, Overweight, and Obese Cohorts
Lucas W. Remedios, Chloe Cho, Trent M. Schwartz +10
Purpose: Although elevated BMI is a well-known risk factor for type 2 diabetes, the disease's presence in some lean adults and absence in others with obesity suggests that detailed…
Multipath cycleGAN for harmonization of paired and unpaired low-dose lung computed tomography reconstruction kernels
Aravind R. Krishnan, Thomas Z. Li, Lucas W. Remedios +12
Reconstruction kernels in computed tomography (CT) affect spatial resolution and noise characteristics, introducing systematic variability in quantitative imaging measurements such…
Investigating the impact of kernel harmonization and deformable registration on inspiratory and expiratory chest CT images for people with COPD
Aravind R. Krishnan, Yihao Liu, Kaiwen Xu +9
Paired inspiratory-expiratory CT scans enable the quantification of gas trapping due to small airway disease and emphysema by analyzing lung tissue motion in COPD patients. Deforma…