409 citations · 2.2k across the 36 of their papers we have counts for
5 papers · 1 filter
Migrating cell clusters as active droplets with asymmetric shape and contact angles
Hanno I. Hennighausen, Jaime A. Espina, Elias H. Barriga +1
During embryonic development and cancer progression, clusters of cells migrate collectively following external cues. Such migrating cell clusters have been modeled as active drople…
Active wetting transition in cell aggregates
MJ Franco-Oñate, Hanno I. Hennighausen, Ricard Alert
During many biological processes, cell aggregates spread on substrates in a process of active wetting. The existing models of tissue spreading, however, do not explicitly capture t…
Quantum motility-induced phase separation
Laurin Brunner, Ricard Alert, Reyhaneh Khasseh +1
Motility-induced phase separation (MIPS) describes a central clustering phenomenon in active matter systems where particles spontaneously separate into dense and dilute phases even…
Bistability of cellular traction on strain-stiffening substrates
Irina Pi-Jaumà, Jaume Casademunt, Ricard Alert
To migrate, cells exert traction forces on the extracellular matrix (ECM) -- a biopolymer network that often exhibits nonlinear strain-stiffening elasticity. Cellular tractions can…
Nonequilibrium noise emerging from broken detailed balance in active gels
Ashot Matevosyan, Frank Jülicher, Ricard Alert
In thermodynamic equilibrium, the fluctuation-dissipation theorem links thermal fluctuations and dissipation. Biological systems, however, are driven out of equilibrium by internal…