238 citations · 413 across the 9 of their papers we have counts for
12 papers · 1 filter
Active wetting transition in cell aggregates
MJ Franco-Oñate, Hanno I. Hennighausen, Ricard Alert
During many biological processes, cell aggregates spread on substrates in a process of active wetting. The existing models of tissue spreading, however, do not explicitly capture t…
Bistability of cellular traction on strain-stiffening substrates
Irina Pi-Jaumà, Jaume Casademunt, Ricard Alert
To migrate, cells exert traction forces on the extracellular matrix (ECM) -- a biopolymer network that often exhibits nonlinear strain-stiffening elasticity. Cellular tractions can…
Modes of Mechanical Guidance of Adhesion-Independent Cell Migration
Hanna Luise Gertack, Peter A. E. Hampshire, Claudia Wohlgemuth +2
Adhesion-independent migration is a prominent mode of cell motility in confined environments, yet the physical principles that guide such movement remain incompletely understood. W…
Curvature induces active velocity waves in rotating multicellular spheroids
Tom Brandstätter, David B. Brückner, Yu Long Han +3
The multicellular organization of diverse systems, such as embryos, intestines and tumours, relies on the coordinated migration of cells in 3D curved environments. In these setting…
Living cells on the move
Ricard Alert, Xavier Trepat
Spectacular collective phenomena such as jamming, turbulence, wetting, and waves emerge when living cells migrate in groups.
Role of Substrate Stiffness in Tissue Spreading: Wetting Transition and Tissue Durotaxis
Ricard Alert, Jaume Casademunt
Living tissues undergo wetting transitions: On a surface, they can either form a droplet-like cell aggregate or spread as a monolayer of migrating cells. Tissue wetting depends not…