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20162020
most citedSeamless phase II/III clinical trials using early outcomes for treatment or subgroup selection: Methods and aspects of their implementation

1 citations · 1 across the 3 of their papers we have counts for

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q-bio.QM2016

Systematic reviews in paediatric multiple sclerosis and Creutzfeldt-Jakob disease exemplify shortcomings in methods used to evaluate therapies in rare conditions

Steffen Unkel, Christian Röver, Nigel Stallard +4

BACKGROUND: Randomized controlled trials (RCTs) are the gold standard design of clinical research to assess interventions. However, RCTs cannot always be applied for practical or e…