93 citations · 624 across the 32 of their papers we have counts for
32 papers
A kinetic model of shear-induced rupture of short dsDNA
Ayman Hussein, Ralf Bundschuh
Force-induced dissociation of short double-stranded DNA (dsDNA) is central to single-molecule biophysics and DNA nanotechnology, yet a physically grounded kinetic description of sh…
Computational modeling of RNA-protein binding interactions under an external force
Danielle Wampler, Ralf Bundschuh
RNA binding proteins play a crucial role in post-transcriptional gene regulation by controlling the transport, processing, and translation of their target RNAs. Post-transcriptiona…
A quantitative model for a nanoscale switch accurately predicts thermal actuation behavior
Kyle Crocker, Joshua Johnson, Wolfgang Pfeifer +2
Manipulation of temperature can be used to actuate DNA origami nano-hinges containing gold nanoparticles. We develop a physical model of this system that uses partition function an…
Potential evolutionary advantage of a dissociative search mechanism in DNA mismatch repair
Kyle Crocker, James London, Andrés Medina +2
Protein complexes involved in DNA mismatch repair appear to diffuse along dsDNA in order to locate a hemimethylated incision site via a dissociative mechanism. Here, we study the p…
On the behavior of random RNA secondary structures near the glass transition
William D. Baez, Kay Jörg Wiese, Ralf Bundschuh
RNA forms elaborate secondary structures through intramolecular base pairing. These structures perform critical biological functions within each cell. Due to the availability of a…
The exon junction complex undergoes a compositional switch that alters mRNP structure and nonsense-mediated mRNA decay activity
Justin W. Mabin, Lauren A. Woodward, Robert Patton +5
The exon junction complex (EJC) deposited upstream of mRNA exon junctions shapes structure, composition and fate of spliced mRNA ribonucleoprotein particles (mRNPs). To achieve thi…