81 citations · 136 across the 5 of their papers we have counts for
4 papers · 1 filter
Natural cubic splines for the analysis of Alzheimer's clinical trials
M. C. Donohue, O. Langford, P. Insel +6
Mixed model repeated measures (MMRM) is the most common analysis approach used in clinical trials for Alzheimer's disease and other progressive diseases measured with continuous ou…
The relative efficiency of time-to-progression and continuous measures of cognition in pre-symptomatic Alzheimer's
Dan Li, Samuel Iddi, Paul S. Aisen +2
Pre-symptomatic (or Preclinical) Alzheimer's Disease is defined by biomarker evidence of fibrillar amyloid beta pathology in the absence of clinical symptoms. Clinical trials in th…
Bayesian latent time joint mixed effect models for multicohort longitudinal data
Dan Li, Samuel Iddi, Wesley K. Thompson +1
Characterization of long-term disease dynamics, from disease-free to end-stage, is integral to understanding the course of neurodegenerative diseases such as Parkinson's and Alzhei…
Regression of ranked responses when raw responses are censored
Michael C. Donohue, Anthony C. Gamst, Robert A. Rissman +1
We discuss semiparametric regression when only the ranks of responses are observed. The model is , where is the unobs…