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physics.med-ph2021
Modeling of cellular response after FLASH irradiation: a quantitative analysis based on the radiolytic oxygen depletion hypothesis
Hongyu Zhu, Junli Li, Xiaowu Deng +3
Purpose: Recent studies suggest ultra-high dose rate (FLASH) irradiation can spare normal tissues from radiotoxicity, while efficiently controlling the tumor, and this is known as…
physics.med-ph2020★ 11 cited
Oxygen depletion hypothesis remains controversial: a mathematical model of oxygen depletion during FLASH radiation
Ankang Hu, Rui Qiu, Zhen Wu +3
Background: Experiments have reported low normal tissue toxicities during FLASH radiation, but the mechanism has not been elaborated. Several hypotheses have been proposed to expla…