activity
20012023
most citedCharacterizing microstructure of living tissues with time-dependent diffusion

359 citations · 2.3k across the 33 of their papers we have counts for

collaborators

34 papers

physics.med-ph2023★ 29 cited

Mapping tissue microstructure of brain white matter in vivo in health and disease using diffusion MRI

Ying Liao, Santiago Coelho, Jenny Chen +7

Diffusion magnetic resonance imaging offers unique in vivo sensitivity to tissue microstructure in brain white matter, which undergoes significant changes during development and is…

physics.med-ph2023★ 23 cited

Optimization and Validation of the DESIGNER dMRI preprocessing pipeline in white matter aging

Jenny Chen, Benjamin Ades-Aron, Hong-Hsi Lee +5

Various diffusion MRI (dMRI) preprocessing pipelines are currently available to yield more accurate diffusion parameters. Here, we evaluated accuracy and robustness of the optimize…

physics.bio-ph2022★ 2 cited

Reproducibility of the Standard Model of diffusion in white matter on clinical MRI systems

Santiago Coelho, Steven H. Baete, Gregory Lemberskiy +5

Estimating intra- and extra-axonal microstructure parameters, such as volume fractions and diffusivities, has been one of the major efforts in brain microstructure imaging with MRI…

physics.med-ph2021★ 198 cited

Neurite Exchange Imaging (NEXI): A minimal model of diffusion in gray matter with inter-compartment water exchange

Ileana O. Jelescu, Alexandre de Skowronski, Françoise Geffroy +2

Biophysical models of diffusion in white matter are based on what is now commonly referred to as the "Standard Model" (SM) of non-exchanging anisotropic Gaussian compartments. In t…

physics.med-ph2020★ 50 cited

Realistic Microstructure Simulator (RMS): Monte Carlo simulations of diffusion in three-dimensional cell segmentations of microscopy images

Hong-Hsi Lee, Els Fieremans, Dmitry S Novikov

Background: Monte Carlo simulations of diffusion are commonly used as a model validation tool as they are especially suitable for generating the diffusion MRI signal in complicated…

physics.med-ph2020★ 75 cited

The impact of realistic axonal shape on axon diameter estimation using diffusion MRI

Hong-Hsi Lee, Sune N. Jespersen, Els Fieremans +1

To study axonal microstructure with diffusion MRI, axons are typically modeled as straight impermeable cylinders, whereby the transverse diffusion MRI signal can be made sensitive…