25 citations · 54 across the 10 of their papers we have counts for
11 papers
CryoChains: Heterogeneous Reconstruction of Molecular Assembly of Semi-flexible Chains from Cryo-EM Images
Bongjin Koo, Julien Martel, Ariana Peck +3
Cryogenic electron microscopy (cryo-EM) has transformed structural biology by allowing to reconstruct 3D biomolecular structures up to near-atomic resolution. However, the 3D recon…
Anomalous Electronic Transport in High Mobility Corbino Rings
Sujatha Vijayakrishnan, F. Poitevin, Oulin Yu +8
We report low-temperature electronic transport measurements performed in two multi-terminal Corbino samples formed in GaAs/Al-GaAs two-dimensional electron gases (2DEG) with both u…
AlignOT: An optimal transport based algorithm for fast 3D alignment with applications to cryogenic electron microscopy density maps
A. Tajmir Riahi, G. Woollard, F. Poitevin +2
Aligning electron density maps from Cryogenic electron microscopy (cryo-EM) is a first key step for studying multiple conformations of a biomolecule. As this step remains costly an…
Amortized Inference for Heterogeneous Reconstruction in Cryo-EM
Axel Levy, Gordon Wetzstein, Julien Martel +2
Cryo-electron microscopy (cryo-EM) is an imaging modality that provides unique insights into the dynamics of proteins and other building blocks of life. The algorithmic challenge o…
Heterogeneous reconstruction of deformable atomic models in Cryo-EM
Youssef Nashed, Ariana Peck, Julien Martel +6
Cryogenic electron microscopy (cryo-EM) provides a unique opportunity to study the structural heterogeneity of biomolecules. Being able to explain this heterogeneity with atomic mo…
CryoAI: Amortized Inference of Poses for Ab Initio Reconstruction of 3D Molecular Volumes from Real Cryo-EM Images
Axel Levy, Frédéric Poitevin, Julien Martel +6
Cryo-electron microscopy (cryo-EM) has become a tool of fundamental importance in structural biology, helping us understand the basic building blocks of life. The algorithmic chall…
Deep Generative Modeling for Volume Reconstruction in Cryo-Electron Microscopy
Claire Donnat, Axel Levy, Frederic Poitevin +2
Recent breakthroughs in high-resolution imaging of biomolecules in solution with cryo-electron microscopy (cryo-EM) have unlocked new doors for the reconstruction of molecular volu…
End-to-End Simultaneous Learning of Single-particle Orientation and 3D Map Reconstruction from Cryo-electron Microscopy Data
Youssef S. G. Nashed, Frederic Poitevin, Harshit Gupta +4
Cryogenic electron microscopy (cryo-EM) provides images from different copies of the same biomolecule in arbitrary orientations. Here, we present an end-to-end unsupervised approac…
Estimation of Orientation and Camera Parameters from Cryo-Electron Microscopy Images with Variational Autoencoders and Generative Adversarial Networks
Nina Miolane, Frédéric Poitevin, Yee-Ting Li +1
Cryo-electron microscopy (cryo-EM) is capable of producing reconstructed 3D images of biomolecules at near-atomic resolution. As such, it represents one of the most promising imagi…
Intermolecular correlations are necessary to explain diffuse scattering from protein crystals
Ariana Peck, Frédéric Poitevin, Thomas J. Lane
Conformational changes drive protein function, including catalysis, allostery, and signaling. X-ray diffuse scattering from protein crystals has frequently been cited as a probe of…
Beyond Poisson-Boltzmann: Numerical sampling of charge density fluctuations
Frédéric Poitevin, Marc Delarue, Henri Orland
We present a method aimed at sampling charge density fluctuations in Coulomb systems. The derivation follows from a functional integral representation of the partition function in…