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Reconstruction of Mutation Laws in Heterogeneous Tumours with Local and Nonlocal Dynamics
Maher Alwuthaynani, Raluca Eftimie, Dumitru Trucu
Cancer cell mutations occur when cells undergo multiple cell divisions, and these mutations can be spontaneous or environmentally-induced. The mechanisms that promote and sustain t…
Mathematical modelling of glioblastomas invasion within the brain: a 3D multi-scale moving-boundary approach
Szabolcs Suveges, Kismet Hossain-Ibrahim, J. Douglas Steele +2
Brain-related experiments are limited by nature, and so biological insights are often restricted or absent. This is particularly problematic in the context of brain cancers, which…
Re-polarisation of macrophages within a multi-scale moving boundary tumour invasion model
Szabolcs Suveges, Raluca Eftimie, Dumitru Trucu
Cancer invasion of the surrounding tissue is a multiscale process that involves not only tumour cells but also other immune cells in the environment, such as the tumour-associated…
A multiscale mathematical model of tumour invasive growth
Lu Peng, Dumitru Trucu, Ping Lin +2
Known as one of the hallmarks of cancer [30], cancer cell invasion of human body tissue is a complicated spatio-temporal multiscale process which enables a localised solid tumour t…