1.3k citations · 2.1k across the 39 of their papers we have counts for
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q-bio.GN2020★ 23 cited
Circuits with broken fibration symmetries perform core logic computations in biological networks
Ian Leifer, Flaviano Morone, Saulo D. S. Reis +3
We show that logic computational circuits in gene regulatory networks arise from a fibration symmetry breaking in the network structure. From this idea we implement a constructive…
q-bio.MN2020★ 48 cited
Fibration symmetries uncover the building blocks of biological networks
Flaviano Morone, Ian Leifer, Hernan A. Makse
A major ambition of systems science is to uncover the building blocks of any biological network to decipher how cellular function emerges from their interactions. Here, we introduc…