2 papers
q-bio.GN2025
Finding low-complexity DNA sequences with longdust
Heng Li, Brian Li
Motivation: Low-complexity (LC) DNA sequences are compositionally repetitive sequences that are often associated with spurious homologous matches and variant calling artifacts. Whi…
q-bio.GN2025
Improving spliced alignment by modeling splice sites with deep learning
Siying Yang, Neng Huang, Heng Li
Motivation: Spliced alignment refers to the alignment of messenger RNA (mRNA) or protein sequences to eukaryotic genomes. It plays a critical role in gene annotation and the study…