3 papers
q-bio.GN2017
Reconstructing antibody repertoires from error-prone immunosequencing datasets
Alexander Shlemov, Sergey Bankevich, Andrey Bzikadze +3
Transforming error-prone immunosequencing datasets into antibody repertoires is a fundamental problem in immunogenomics, and a prerequisite for studies of immune responses. Althoug…
q-bio.QM2017
Two-exponential models of gene expression patterns for noisy experimental data
Theodore Alexandrov, Nina Golyandina, David Holloway +2
Motivation: Spatial pattern formation of the primary anterior-posterior morphogenetic gradient of the transcription factor Bicoid (Bcd) has been studied experimentally and computat…
q-bio.GN2016
New algorithmic challenges of adaptive immune repertoire construction
Alexander Shlemov, Sergey Bankevich, Andrey Bzikadze +1
Motivation: The analysis of antibodies and T-cell receptors (TCRs) concentrations in serum is a fundamental problem in immunoinformatics. Repertoire construction is a preliminary s…