108 citations · 167 across the 7 of their papers we have counts for
7 papers
Current and future directions in network biology
Marinka Zitnik, Michelle M. Li, Aydin Wells +34
Network biology is an interdisciplinary field bridging computational and biological sciences that has proved pivotal in advancing the understanding of cellular functions and diseas…
AptaBlocks Online - A web-based toolkit for the in-silico assembly of RNA complexes
Jan Hoinka, Yijie Wang, Teresa M. Przytycka
Summary: The AptaBlocks Web Interface is focused on providing graphical, intuitive, and platform independent access to AptaBlocks, an experimentally validated algorithmic approach…
BeWith: A Between-Within Method to Discover Relationships between Cancer Modules via Integrated Analysis of Mutual Exclusivity, Co-occurrence and Functional Interactions
Phuong Dao, Yoo-Ah Kim, Damian Wojtowicz +3
The analysis of the mutational landscape of cancer, including mutual exclusivity and co-occurrence of mutations, has been instrumental in studying the disease. We hypothesized that…
NetREX: Network Rewiring using EXpression - Towards Context Specific Regulatory Networks
Yijie Wang, Dong-Yeon Cho, Hangnoh Lee +3
Understanding gene regulation is a fundamental step towards understanding of how cells function and respond to environmental cues and perturbations. An important step in this direc…
WeSME: Uncovering Mutual Exclusivity of Cancer Drivers and Beyond
Yoo-Ah Kim, Sanna Madan, Teresa M. Przytycka
Mutual exclusivity is a widely recognized property of many cancer drivers. Knowledge about these relationships can provide important insights into cancer drivers, cancer-driving pa…
AptaTRACE: Elucidating Sequence-Structure Binding Motifs by Uncovering Selection Trends in HT-SELEX Experiments
Phuong Dao, Jan Hoinka, Yijie Wang +7
Aptamers, short synthetic RNA/DNA molecules binding specific targets with high affinity and specificity, are utilized in an increasing spectrum of bio-medical applications. Aptamer…
Zen and the Science of Pattern Identification: An Inquiry into Bayesian Skepticism
Deborah A. Striegel, Damian Wojtowicz, Teresa M. Przytycka +1
Finding patterns in data is one of the most challenging open questions in information science. The number of possible relationships scales combinatorially with the size of the data…