90 citations · 154 across the 4 of their papers we have counts for
5 papers
Waveforms of molecular oscillations reveal circadian timekeeping mechanisms
Hang-Hyun Jo, Yeon Jeong Kim, Jae Kyoung Kim +3
Circadian clocks play a pivotal role in orchestrating numerous physiological and developmental events. Waveform shapes of the oscillations of protein abundances can be informative…
Reduction for stochastic biochemical reaction networks with multiscale conservations
Jae Kyoung Kim, Grzegorz A. Rempala, Hye-Won Kang
Biochemical reaction networks frequently consist of species evolving on multiple timescales. Stochastic simulations of such networks are often computationally challenging and there…
Protein sequestration versus Hill-type repression in circadian clock models
Jae Kyoung Kim
Circadian (~24hr) clocks are self-sustained endogenous oscillators with which organisms keep track of daily and seasonal time. Circadian clocks frequently rely on interlocked trans…
The validity of quasi steady-state approximations in discrete stochastic simulations
Jae Kyoung Kim, Krešimir Josić, Matthew R. Bennett
In biochemical networks, reactions often occur on disparate timescales and can be characterized as either "fast" or "slow." The quasi-steady state approximation (QSSA) utilizes tim…
Molecular mechanisms that regulate the coupled period of the mammalian circadian clock
Jae Kyoung Kim, Zachary P. Kilpatrick, Matthew R. Bennett +1
In mammals, most cells in the brain and peripheral tissues generate circadian (~24hr) rhythms autonomously. These self-sustained rhythms are coordinated and entrained by a master c…