12 citations · 20 across the 5 of their papers we have counts for
3 papers · 1 filter
A frame-based representation of genomic sequences for removing errors and rare variant detection in NGS data
Raunaq Malhotra, Manjari Mukhopadhyay, Mary Poss +1
We propose a frame-based representation of k-mers for detecting sequencing errors and rare variants in next generation sequencing data obtained from populations of closely related…
Separating Putative Pathogens from Background Contamination with Principal Orthogonal Decomposition: Evidence for Leptospira in the Ugandan Neonatal Septisome
Steven J. Schiff, Julius Kiwanuka, Gina Riggio +14
Neonatal sepsis (NS) is responsible for over a 1 million yearly deaths worldwide. In the developing world NS is often treated without an identified microbial pathogen. Amplicon seq…
Clustering pipeline for determining consensus sequences in targeted next-generation sequencing
Raunaq Malhotra, Daniel Elleder, Le Bao +3
Analyses of targeted genomic sequencing data from next-generation-sequencing (NGS) technologies typically involves mapping reads to a reference sequence or clustering reads. For a…