activity
20132023
most citedPooling single-cell recordings: Scalable inference through heterogeneous kinetics

162 citations · 253 across the 11 of their papers we have counts for

collaborators

12 papers

q-bio.MN2023

A local polynomial moment approximation for compartmentalised biochemical systems

Tommaso Bianucci, Christoph Zechner

Compartmentalised biochemical reactions are a ubiquitous building block of biological systems. The interplay between chemical and compartmental dynamics can drive rich and complex…

q-bio.MN2022

Dynamic Information Transfer in Stochastic Biochemical Networks

Anne-Lena Moor, Christoph Zechner

We develop numerical and analytical approaches to calculate mutual information between complete paths of two molecular components embedded into a larger reaction network. In partic…

math.OC2021

Design of a synthetic integral feedback circuit: dynamic analysis and DNA implementation

Corentin Briat, Christoph Zechner, Mustafa Khammash

The design and implementation of regulation motifs ensuring robust perfect adaptation are challenging problems in synthetic biology. Indeed, the design of high-yield robust metabol…

q-bio.QM2020★ 30 cited

Stochastic reaction networks in dynamic compartment populations

Lorenzo Duso, Christoph Zechner

Compartmentalization of biochemical processes underlies all biological systems, from the organelle to the tissue scale. Theoretical models to study the interplay between noisy reac…

nlin.AO2019

The gift of gab: probing the limits of dynamic concentration-sensing across a network of communicating cells

Mohammadreza Bahadorian, Christoph Zechner, Carl Modes

Many systems in biology and beyond employ collaborative, collective communication strategies for improved efficiency and adaptive benefit. One such paradigm of particular interest…

q-bio.MN2019

Moment-based analysis of biochemical networks in a heterogeneous population of communicating cells

David T. Gonzales, T-Y Dora Tang, Christoph Zechner

Cells can utilize chemical communication to exchange information and coordinate their behavior in the presence of noise. Communication can reduce noise to shape a collective respon…