78 citations · 144 across the 7 of their papers we have counts for
4 papers · 1 filter
Dynamic disorder in simple enzymatic reactions induces stochastic amplification of substrate
Ankit Gupta, Andreas Milias-Argeitis, Mustafa Khammash
A growing amount of evidence points to the fact that many enzymes exhibit fluctuations in their catalytic activity, which are associated with conformational changes on a broad rang…
Parameter inference method for stochastic single-cell dynamics from tree-structured data
Irena Kuzmanovska, Andreas Milias-Argeitis, Christoph Zechner +1
With the advance of experimental techniques such as time-lapse fluorescence microscopy, the availability of single-cell trajectory data has vastly increased, and so has the demand…
Variance reduction for steady-state simulation and sensitivity analysis of stochastic chemical systems
Andreas Milias-Argeitis, John Lygeros, Mustafa Khammash
We address the problem of estimating steady-state quantities associated to systems of stochastic chemical kinetics. In most cases of interest these systems are analytically intract…
Designing Experiments to Understand the Variability in Biochemical Reaction Networks
Jakob Ruess, Andreas Milias-Argeitis, John Lygeros
Exploiting the information provided by the molecular noise of a biological process has proven to be valuable in extracting knowledge about the underlying kinetic parameters and sou…