51 citations · 90 across the 5 of their papers we have counts for
5 papers
A Community-Developed Open-Source Computational Ecosystem for Big Neuro Data
Randal Burns, Eric Perlman, Alex Baden +27
Big imaging data is becoming more prominent in brain sciences across spatiotemporal scales and phylogenies. We have developed a computational ecosystem that enables storage, visual…
A Large Deformation Diffeomorphic Approach to Registration of CLARITY Images via Mutual Information
Kwame S. Kutten, Nicolas Charon, Michael I. Miller +7
CLARITY is a method for converting biological tissues into translucent and porous hydrogel-tissue hybrids. This facilitates interrogation with light sheet microscopy and penetratio…
Deformably Registering and Annotating Whole CLARITY Brains to an Atlas via Masked LDDMM
Kwame S. Kutten, Joshua T. Vogelstein, Nicolas Charon +3
The CLARITY method renders brains optically transparent to enable high-resolution imaging in the structurally intact brain. Anatomically annotating CLARITY brains is necessary for…
Self-tracking Energy Transfer for Neural Stimulation in Untethered Mice
John S. Ho, Yuji Tanabe, Shrivats Mohan Iyer +5
Optical or electrical stimulation of neural circuits in mice during natural behavior is an important paradigm for studying brain function. Conventional systems for optogenetics and…
The Open Connectome Project Data Cluster: Scalable Analysis and Vision for High-Throughput Neuroscience
Randal Burns, William Gray Roncal, Dean Kleissas +17
We describe a scalable database cluster for the spatial analysis and annotation of high-throughput brain imaging data, initially for 3-d electron microscopy image stacks, but for t…