3 papers
q-bio.NC2018
A Community-Developed Open-Source Computational Ecosystem for Big Neuro Data
Randal Burns, Eric Perlman, Alex Baden +27
Big imaging data is becoming more prominent in brain sciences across spatiotemporal scales and phylogenies. We have developed a computational ecosystem that enables storage, visual…
cs.CV2016
A Large Deformation Diffeomorphic Approach to Registration of CLARITY Images via Mutual Information
Kwame S. Kutten, Nicolas Charon, Michael I. Miller +7
CLARITY is a method for converting biological tissues into translucent and porous hydrogel-tissue hybrids. This facilitates interrogation with light sheet microscopy and penetratio…
q-bio.QM2016
Deformably Registering and Annotating Whole CLARITY Brains to an Atlas via Masked LDDMM
Kwame S. Kutten, Joshua T. Vogelstein, Nicolas Charon +3
The CLARITY method renders brains optically transparent to enable high-resolution imaging in the structurally intact brain. Anatomically annotating CLARITY brains is necessary for…