2 papers
q-bio.QM2025
ProtT-Affinity: Sequence-Based Protein-Protein Binding Affinity Prediction Using ProtT5 Embeddings
Hongfu Lou
Predicting the binding affinity of protein protein complexes directly from sequence remains a challenging problem, particularly in the absence of reliable structural information. H…
q-bio.QM2025
MP-GCAN: a highly accurate classifier for -helical membrane proteins and -barrel proteins
Kunyang Li, Hongfu Lou, Dinan Peng
Membrane protein classification is a fundamental task in structural bioinformatics, critical to understanding protein functions and accelerating drug discovery. In this study, we p…