5 papers
Integrated Open-Source Framework for Simulation of Transcatheter Pulmonary Valves in Native Right Ventricular Outflow Tracts
Christopher N. Zelonis, Jalaj Maheshwari, Wensi Wu +14
Background - Pulmonary insufficiency is a consequence of transannular patch repair in Tetralogy of Fallot (ToF), leading to late morbidity and mortality. Transcatheter native outfl…
Simulation of Repair on Dynamic Patient-Specific Left Atrioventricular Valve Models
Stephen Ching, Christopher Zelonis, Christian Herz +12
Purpose: To develop and evaluate a dynamic, image-derived patient-specific physical simulation platform for the assessment of left atrioventricular valve (LAVV) repair strategies i…
Simulation of Transcatheter Therapies for Atrioventricular Valve Regurgitation in an Open-Source Finite Element Simulation Framework
Seda Aslan, Nicolas R. Mangine, Devin W. Laurence +8
Purpose: Transcatheter edge-to-edge repair (TEER) and annuloplasty devices are increasingly used to treat mitral valve regurgitation, yet their mechanical effects and interactions…
ADEPT: A Noninvasive Method for Determining Elastic Parameters of Valve Tissue
Wensi Wu, Mitchell Daneker, Christian Herz +5
Computer simulation of "virtual interventions" may inform optimal valve repair for a given patient prior to intervention. However, the paucity of noninvasive methods to determine i…
Effect of Parametric Variation of Chordae Tendineae Structure on Simulated Atrioventricular Valve Closure
Nicolas R. Mangine, Devin W. Laurence, Patricia M. Sabin +9
Many approaches have been used to model chordae tendineae geometries in finite element simulations of atrioventricular heart valves. Unfortunately, current "functional" chordae ten…