2 papers
q-bio.BM2021
Tetrameric UvrD helicase is located at the E. coli replisome due to frequent replication blocks
Adam J. M Wollman, Aisha H. Syeda, Andrew Leech +4
DNA replication in all organisms must overcome nucleoprotein blocks to complete genome duplication. Accessory replicative helicases in Escherichia coli, Rep and UvrD, help replicat…
q-bio.SC2016
Single-molecule observation of DNA replication repair pathways in E. coli
Adam J. M. Wollman, Aisha H. Syeda, Peter McGlynn +1
The method of action of many antibiotics is to interfere with DNA replication - quinolones trap DNA gyrase and topoisomerase proteins onto DNA while metronidazole causes single and…