activity
20162022
most citedTuning environmental timescales to evolve and maintain generalists

58 citations · 79 across the 6 of their papers we have counts for

collaborators

6 papers

cond-mat.soft2022★ 1 cited

Learning to learn: Non-equilibrium design protocols for adaptable materials

Martin J. Falk, Jiayi Wu, Ayanna Matthews +5

Evolution in time-varying environments naturally leads to adaptable biological systems that can easily switch functionalities. Advances in the synthesis of environmentally-responsi…

physics.bio-ph2021★ 9 cited

Inferring couplings in networks across order-disorder phase transitions

Vudtiwat Ngampruetikorn, Vedant Sachdeva, Johanna Torrence +3

Statistical inference is central to many scientific endeavors, yet how it works remains unresolved. Answering this requires a quantitative understanding of the intrinsic interplay…

q-bio.PE2019★ 58 cited

Tuning environmental timescales to evolve and maintain generalists

Vedant Sachdeva, Kabir Husain, Jiming Sheng +2

Natural environments can present diverse challenges, but some genotypes remain fit across many environments. Such `generalists' can be hard to evolve, out-competed by specialists f…

q-bio.BM2016★ 1 cited

Hemoglobin Strain Field Waves and Allometric Functionality

Vedant Sachdeva, J. C. Phillips

Hemoglobin (Hgb) forms tetramers (dimerized dimers), which enhance its globular stability and may also facilitate small gas molecule transport, as shown by recent all-atom Newtonia…

q-bio.OT2016★ 8 cited

Oxygen Channels and Fractal Wave-Particle Duality in the Evolution of Myoglobin and Neuroglobin

Vedant Sachdeva, James C. Phillips

The evolution of terrestrial and aquatic wild type (WT) globins is dominated by changes in two proximate - distal Histidine ligand exit channels, here monitored quantitatively by h…

q-bio.OT2016★ 2 cited

Hidden Thermodynamic Information in Protein Amino Acid Mutation Tables

V. Sachdeva, J. C. Phillips

We combine the standard 1992 20x20 substitution matrix based on block alignment, BLOSUM62, with the standard 1982 amino acid hydropathicity scale KD as well as the modern 2007 hydr…