5 papers
Comprehensive Multimodal and Multiscale Analysis of Alzheimer Disease in 5xFAD Mice: Optical Spectroscopies, TEM, Neuropathological, and Behavioral Investigations
Dhruvil Solanki, Ishmael Apachigawo, Sazzad Khan +8
Alzheimer disease (AD) is considered one of the leading causes of death in the United States, and there is no effective cure for it. Understanding the neuropathological mechanisms…
Finer-Focused Partial Wave Spectroscopy (ff-PWS) and Detection of Cancer Stages From Human Tissue Samples
Dhruvil Solanki, Prakash Adhikari, Ishmael Apachigawo +2
The progression of cancer is associated with different genetic and epigenetic events which result in nano to microscale structural alterations in cells/tissue. However, these struc…
Photonics detection of molecular-specific spatial structural alterations in cell nuclei due to chronic alcoholism and probiotics treatments on colon cancer via a light localization method using confocal imaging
Ishmael Apachigawo, Dhruvil Solanki, Santanu Maity +3
Photonics/light localization techniques are important in understanding the structural changes in biological tissues at the nano- to sub-micron scale. It is now known that structura…
Optical detection of the spatial structural alteration in the human brain tissues and cells and DNA and chromatin due to Parkinsons disease
Fatemah Alharthi, Dhruvil Solanki, Ishmael Apachigawo +3
Parkinsons disease (PD) is considered one of the most frequent neurological diseases in the world. There is a need to study the early and efficient biomarkers of Parkinsons, such a…
Dual Photonics Probing of Nano- to Submicron-Scale Structural Alterations in Human Brain Tissues or Cells and Chromatin or DNA with the Progression of Alzheimers Disease
Fatemah Alharthi, Ishmael Apachigawo, Dhruvil Solanki +4
Understanding alterations in structural disorders in tissue or cells or building blocks, such as DNA or chromatin in the human brain, at the nano to submicron level provides us wit…