6 papers
Comprehensive Multimodal and Multiscale Analysis of Alzheimer Disease in 5xFAD Mice: Optical Spectroscopies, TEM, Neuropathological, and Behavioral Investigations
Dhruvil Solanki, Ishmael Apachigawo, Sazzad Khan +8
Alzheimer disease (AD) is considered one of the leading causes of death in the United States, and there is no effective cure for it. Understanding the neuropathological mechanisms…
Finer-Focused Partial Wave Spectroscopy (ff-PWS) and Detection of Cancer Stages From Human Tissue Samples
Dhruvil Solanki, Prakash Adhikari, Ishmael Apachigawo +2
The progression of cancer is associated with different genetic and epigenetic events which result in nano to microscale structural alterations in cells/tissue. However, these struc…
Photonics detection of molecular-specific spatial structural alterations in cell nuclei due to chronic alcoholism and probiotics treatments on colon cancer via a light localization method using confocal imaging
Ishmael Apachigawo, Dhruvil Solanki, Santanu Maity +3
Photonics/light localization techniques are important in understanding the structural changes in biological tissues at the nano- to sub-micron scale. It is now known that structura…
Optical probing of fractal and multifractal connection to structural disorder in weakly optical disordered media: Application to cancer detection
Santanu Maity, Mousa Alrubayan, Ishmael Apachigwao +2
The light scattering experiment establishes a relationship between refractive index fluctuations and fractal dimension in weakly scattering tissue-like media. Based on the box-coun…
Optical detection of the spatial structural alteration in the human brain tissues and cells and DNA and chromatin due to Parkinsons disease
Fatemah Alharthi, Dhruvil Solanki, Ishmael Apachigawo +3
Parkinsons disease (PD) is considered one of the most frequent neurological diseases in the world. There is a need to study the early and efficient biomarkers of Parkinsons, such a…
Dual Photonics Probing of Nano- to Submicron-Scale Structural Alterations in Human Brain Tissues or Cells and Chromatin or DNA with the Progression of Alzheimers Disease
Fatemah Alharthi, Ishmael Apachigawo, Dhruvil Solanki +4
Understanding alterations in structural disorders in tissue or cells or building blocks, such as DNA or chromatin in the human brain, at the nano to submicron level provides us wit…