65 citations · 170 across the 11 of their papers we have counts for
12 papers
Shape optimization of slip-driven axisymmetric microswimmers
Ruowen Liu, Hai Zhu, Hanliang Guo +2
In this work, we develop a computational framework that aims at simultaneously optimizing the shape and the slip velocity of an axisymmetric microswimmer suspended in a viscous flu…
Hydrodynamic bound states of rotating micro-cylinders in a confining geometry
Hanliang Guo, Yi Man, Hai Zhu
Many micro-swimmers propel themselves by rotating micro-cylindrical organelles such as flagella or cilia. These cylindrical organelles almost never live in free space, yet their mo…
Spontaneous phase coordination and fluid pumping in model ciliary carpets
Anup Kanale, Feng Ling, Hanliang Guo +2
Ciliated tissues such as in the mammalian lungs, brains, and reproductive tracts, are specialized to pump fluid. They generate flows by the collective activity of hundreds of thous…
Optimal Ciliary Locomotion of Axisymmetric Microswimmers
Hanliang Guo, Hai Zhu, Ruowen Liu +2
Many biological microswimmers locomote by periodically beating the densely-packed cilia on their cell surface in a wave-like fashion. While the swimming mechanisms of ciliated micr…
Intracellular coupling modulates biflagellar synchrony
Hanliang Guo, Yi Man, Kirsty Y. Wan +1
Beating flagella exhibit a variety of synchronization modes. This synchrony has long been attributed to hydrodynamic coupling between the flagella. However, recent work with flagel…
Optimal slip velocities of micro-swimmers with arbitrary axisymmetric shapes
Hanliang Guo, Hai Zhu, Ruowen Liu +2
This article presents a computational approach for determining the optimal slip velocities on any given shape of an axisymmetric micro-swimmer suspended in a viscous fluid. The obj…
Simulating cilia-driven mixing and transport in complex geometries
Hanliang Guo, Hai Zhu, Shravan Veerapaneni
Cilia and flagella are self-actuated microtubule-based structures that are present on many cell surfaces, ranging from the outer surface of single-cell organisms to the internal ep…
Instability-driven Oscillations of Elastic Microfilaments
Feng Ling, Hanliang Guo, Eva Kanso
Cilia and flagella are highly conserved slender organelles that exhibit a variety of rhythmic beating patterns from non-planar cone-like motions to planar wave-like deformations. A…
Bistability in the synchronization of actuated microfilaments
Hanliang Guo, Lisa Fauci, Michael Shelley +1
Cilia and flagella are essential building blocks for biological fluid transport and locomotion at the micron scale. They often beat in synchrony and may transition between differen…
Mucociliary Transport in Healthy and Diseased Environments
Hanliang Guo, Eva Kanso
Mucociliary clearance in the lung is the primary defense mechanism that protects the airways from inhaled toxicants and infectious agents. The system consists of a viscoelastic muc…
Evaluating efficiency and robustness in cilia design
Hanliang Guo, Eva Kanso
Motile cilia are used by many eukaryotic cells to transport flow. Cilia-driven flows are important to many physiological functions, yet a deep understanding of the interplay betwee…
Cilia beating patterns are not hydrodynamically optimal
Hanliang Guo, Janna Nawroth, Yang Ding +1
We examine the hydrodynamic performance of two cilia beating patterns reconstructed from experimental data. In their respective natural systems, the two beating patterns correspond…