activity
20162020
most citedUnveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 92 crystal structures

5 citations · 13 across the 8 of their papers we have counts for

collaborators

12 papers

q-bio.BM20202 cited

Review of COVID-19 Antibody Therapies

Jiahui Chen, Kaifu Gao, Rui Wang +2

Under the global health emergency caused by coronavirus disease 2019 (COVID-19), efficient and specific therapies are urgently needed. Compared with traditional small-molecular dru…

q-bio.BM20201 cited

Generative network complex for the automated generation of druglike molecules

Kaifu Gao, Duc D Nguyen, Meihua Tu +1

Current drug discovery is expensive and time-consuming. It remains a challenging task to create a wide variety of novel compounds with desirable pharmacological properties and chea…

q-bio.BM20205 cited

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 92 crystal structures

Duc D Nguyen, Kaifu Gao, Jiahui Chen +2

Currently, there is no effective antiviral drugs nor vaccine for coronavirus disease 2019 (COVID-19) caused by acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Due to its hig…

q-bio.BM2020

Repositioning of 8565 existing drugs for COVID-19

Kaifu Gao, Duc Duy Nguyen, Jiahui Chen +2

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected near 5 million people and led to over 0.3 milli…

math.CO20192 cited

Persistent spectral graph

Rui Wang, Duc Duy Nguyen, Guo-Wei Wei

Persistent homology is constrained to purely topological persistence while multiscale graphs account only for geometric information. This work introduces persistent spectral theory…

q-bio.BM2019

A review of mathematical representations of biomolecules

Duc D Nguyen, Zixuan Cang, Guo-Wei Wei

Recently, machine learning (ML) has established itself in various worldwide benchmarking competitions in computational biology, including Critical Assessment of Structure Predictio…