Dual Graph-Laplacian PCA: A Closed-Form Solution for Bi-clustering to Find "Checkerboard" Structures on Gene Expression Data

Jin-Xing Liu, Chun-Mei Feng, Xiang-Zhen Kong +1

In the context of cancer, internal "checkerboard" structures are normally found in the matrices of gene expression data, which correspond to genes that are significantly up- or dow…