3 papers
q-bio.OT2025
The Hands-On Growth Laws Theory Cookbook
Rossana Droghetti, Mattia Corigliano, Ludovico Calabrese +6
This tutorial covers the emerging field of coarse-grained cellular growth modeling, and aims to bridge the gap between theoretical foundations and practical application. By adoptin…
cond-mat.stat-mech2025
Biologically relevant finite-size effects in a driven lattice gas with particle pausing and dynamical defects
Johannes Keisers, Lorenzo Vito Dal Zovo, Norbert Kern +1
In this article we present a comprehensive study of the totally asymmetric simple exclusion process with pausing particles (pTASEP), a model initially introduced to describe RNAP d…
q-bio.SC2025
Paused in translation: A model for the transcript length-dependent impact of ribosome-targeting antibiotics
Johannes Keisers, Norbert Kern, Luca Ciandrini
Ribosome-targeting antibiotics, such as chloramphenicol, stall elongating ribosomes during protein synthesis, disrupting mRNA translation. These antibiotic-induced pauses occur sto…