11 citations · 11 across the 3 of their papers we have counts for
5 papers
A Hybrid HMM Approach for the Dynamics of DNA Methylation
Charalampos Kyriakopoulos, Pascal Giehr, Alexander Lück +2
The understanding of mechanisms that control epigenetic changes is an important research area in modern functional biology. Epigenetic modifications such as DNA methylation are in…
Lumping the Approximate Master Equation for Multistate Processes on Complex Networks
Gerrit Großmann, Charalampos Kyriakopoulos, Luca Bortolussi +1
Complex networks play an important role in human society and in nature. Stochastic multistate processes provide a powerful framework to model a variety of emerging phenomena such a…
Lumping of Degree-Based Mean Field and Pair Approximation Equations for Multi-State Contact Processes
Charalampos Kyriakopoulos, Gerrit Grossmann, Verena Wolf +1
Contact processes form a large and highly interesting class of dynamic processes on networks, including epidemic and information spreading. While devising stochastic models of such…
H(O)TA: estimation of DNA methylation and hydroxylation levels and efficiencies from time course data
Charalampos Kyriakopoulos, Pascal Giehr, Verena Wolf
Methylation and hydroxylation of cytosines to form 5-methylcytosine (5mC) and 5-droxymethylcytosine (5hmC) belong to the most important epigenetic modifications and their vital rol…
Optimal Observation Time Points in Stochastic Chemical Kinetics
Charalampos Kyriakopoulos, Verena Wolf
Wet-lab experiments, in which the dynamics within living cells are observed, are usually costly and time consuming. This is particularly true if single-cell measurements are obtain…