4 papers
Coarsened mixtures of hierarchical skew normal kernels for flow cytometry analyses
Shai Gorsky, Cliburn Chan, Li Ma
Flow cytometry (FCM) is the standard multi-parameter assay for measuring single cell phenotype and functionality. It is commonly used for quantifying the relative frequencies of ce…
TEAM: A Multiple Testing Algorithm on the Aggregation Tree for Flow Cytometry Analysis
John Pura, Xuechan Li, Cliburn Chan +1
In immunology studies, flow cytometry is a commonly used multivariate single-cell assay. One key goal in flow cytometry analysis is to pinpoint the immune cells responsive to certa…
Bayesian Multi Plate High Throughput Screening of Compounds
Ivo D. Shterev, David B. Dunson, Cliburn Chan +1
High throughput screening of compounds (chemicals) is an essential part of drug discovery [7], involving thousands to millions of compounds, with the purpose of identifying candida…
Bayesian analysis of immune response dynamics with sparse time series data
Fernando V. Bonassi, Cliburn Chan, Mike West
In vaccine development, the temporal profiles of relative abundance of subtypes of immune cells (T-cells) is key to understanding vaccine efficacy. Complex and expensive experiment…