1 citations · 1 across the 1 of their papers we have counts for
4 papers
Parameter estimation in nonlinear mixed effect models based on ordinary differential equations: an optimal control approach
Quentin Clairon, Chloé Pasin, Irene Balelli +2
We present a parameter estimation method for nonlinear mixed effect models based on ordinary differential equations (NLME-ODEs). The method presented here aims at regularizing the…
Multi-type Galton-Watson processes with affinity-dependent selection applied to antibody affinity maturation
Irene Balelli, Vuk Milišić, Gilles Wainrib
We analyze the interactions between division, mutation and selection in a simplified evolutionary model, assuming that the population observed can be classified into fitness levels…
Branching Random Walks on Binary Strings for Evolutionary Processes
Irene Balelli, Vuk Milisic, Gilles Wainrib
In this article, we study branching random walks on graphs modeling division-mutation processes inspired by adaptive immunity. We apply the theory of expander graphs on mutation ru…
Random walks on binary strings applied to the somatic hypermutation of B-cells
Irene Balelli, Vuk Milisic, Gilles Wainrib
Within the germinal center in follicles, B-cells proliferate, mutate and differentiate, while being submitted to a powerful selection~: a micro-evolutionary mechanism at the heart…