4 papers
When Branch-Local Shunting Helps: A Gain-Load-Alignment Principle for Dendritic E/I Networks
Houman Safaai, Maceo Richards, Naeem Khoshnevis +1
Biological neurons combine excitatory and inhibitory (E/I) activity on branched dendrites through shunting, in which inhibition divisively attenuates excitation. Whether this impro…
Synaptic clustering emerges from learning and supports covariance discrimination
Ilenna Simone Jones, Maceo Richards, Houman Safaai +2
Functional synapse clusters (FSCs) are synapses with correlated presynaptic activity that are colocalized on the same neuronal dendritic branch. FSCs have been observed after learn…
Shunting Inhibition and Dendritic Branching Shape Local Credit Assignment
Houman Safaai, Maceo Richards, Bernardo L. Sabatini
Biological neurons assign credit across branching dendrites, where synaptic drive, conductance, local voltage, and somatic teaching signals interact to shape plasticity. We study c…
Credit Assignment via Neural Manifold Noise Correlation
Byungwoo Kang, Maceo Richards, Bernardo Sabatini
Credit assignment--how changes in individual neurons and synapses affect a network's output--is central to learning in brains and machines. Noise correlation, which estimates gradi…