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20152026
most citedAnalysis of stepped wedge cluster randomized trials in the presence of a time-varying treatment effect

71 citations · 105 across the 17 of their papers we have counts for

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Showing 2025Show all

5 papers · 1 filter

stat.ME2025

Robust and Efficient Semiparametric Inference for the Stepped Wedge Design

Fan Xia, K. C. Gary Chan, Emily Voldal +3

Stepped wedge designs (SWDs) are increasingly used to evaluate longitudinal cluster-level interventions but pose substantial challenges for valid inference. Because crossover times…

stat.ME2025

Covariate-adjusted win statistics in randomized clinical trials with ordinal outcomes

Zhiqiang Cao, Scott Zuo, Mary Ryan Baumann +4

Ordinal outcomes are common in clinical settings where they often represent increasing levels of disease progression or different levels of functional impairment. In this article,…

stat.ME2025

Model-robust standardization in stepped wedge cluster randomized trials

Xi Fang, Xueqi Wang, Patrick J. Heagerty +2

Stepped-wedge cluster-randomized trials (SW-CRTs) are widely used in healthcare and implementation science, enabling all clusters to receive the intervention through a staggered ro…

stat.ME2025

Factors affecting power in stepped wedge trials when the treatment effect varies with time

Avi Kenny, Emily C. Voldal, Fan Xia +3

Stepped wedge cluster randomized trials (SW-CRTs) have historically been analyzed using immediate treatment (IT) models, which assume the effect of the treatment is immediate after…

stat.ME2025

A tutorial on conducting sample size and power calculations for detecting treatment effect heterogeneity in cluster randomized trials with linear mixed models

Mary Ryan Baumann, Monica Taljaard, Patrick J. Heagerty +4

Cluster-randomized trials (CRTs) are a well-established class of designs for evaluating community-based interventions. An essential task in planning these trials is determining the…