158 citations · 998 across the 40 of their papers we have counts for
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physics.bio-ph2006★ 158 cited
The thermodynamics of general anesthesia
Thomas Heimburg, Andrew D. Jackson
It is known that the action of general anesthetics is proportional to their partition coefficient in lipid membranes (Meyer-Overton rule). This solubility is, however, directly rel…
physics.bio-ph2006★ 99 cited
On the action potential as a propagating density pulse and the role of anesthetics
Thomas Heimburg, Andrew D. Jackson
The Hodgkin-Huxley model of nerve pulse propagation relies on ion currents through specific resistors called ion channels. We discuss a number of classical thermodynamic findings o…