2 papers
q-bio.BM2026
Persistent Manifold Learning of Protein Properties
Xingjian Xu, Zhe Su, Guo-Wei Wei +1
Predicting how tightly two biomolecules bind remains a major challenge, in part because different interaction classes present dissimilar interfaces, from compact metal-coordinated…
q-bio.BM2024
PLD-Tree: Persistent Laplacian Decision Tree for Protein-Protein Binding Free Energy Prediction
Xingjian Xu, Jiahui Chen, Chunmei Wang
Recent advances in topology-based modeling have accelerated progress in physical modeling and molecular studies, including applications to protein-ligand binding affinity. In this…